Designing Protein Binders Using the Generative Model Proteina-Complexa

Developing new protein-based therapies and catalysts involves the challenging task of designing protein binders, or proteins that bind to a target protein or…

Developing new protein-based therapies and catalysts involves the challenging task of designing protein binders, or proteins that bind to a target protein or small molecule. The search space for possible amino acid sequence permutations and resulting 3D protein structures for a designed binder is vast, and achieving strong, specific binding requires careful optimization of the interactions between…

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